Cyclin B1 anticorps (AA 1-433) (Fluoro488)

N° du produit ABIN7982123

Cet anticorps anti-Cyclin B1 Polyclonal Lapin conjugué à Fluoro488 (ABIN7982123) détecte spécifiquement Cyclin B1 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Cyclin B1 anticorps (AA 1-433) (Fluoro488) (ABIN7982123)

Antigène: Cyclin B1 (CCNB1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin B1 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-Cyclin B1 anticorps (Fluoro488)

Épitope: AA 1-433

Fonction: Anti-Cyclin B1/CCNB1 Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human Cyclin B1 shares 86%,85% amino acid (aa) sequences identity with mouse,rat Cyclin B1,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Cyclin B1 recombinant protein (Position: M1-V433). Human Cyclin B1 shares 86% and 85% amino acid (aa) sequences identity with mouse and rat Cyclin B1, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Cyclin B1

Antigène: Cyclin B1 (CCNB1)

Autre désignation: CCNB

Sujet:

Background: CCNB also known as Cyclin B1, is a protein that in humans is encoded by the CCNB1 gene, and it is mapped to 5q13.2. The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. CCNB contributes to the switch-like all or none behavior of the cell in deciding to commit to mitosis. Its activation is well-regulated, and positive feedback loops ensure that once the cyclin B1-Cdk1 complex is activated, it is not deactivated.

Gene Full Name: cyclin B1

Sequence Similarities: Belongs to the cyclin family. Cyclin AB subfamily.

ID gène: 891

UniProt: P14635

Pathways: Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase