CDK5 anticorps (AA 1-226) (APC)

N° du produit ABIN7982370

Cet anticorps Lapin Polyclonal détecte spécifiquement CDK5 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CDK5 anticorps (AA 1-226) (APC) (ABIN7982370)

Antigène: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK5 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-CDK5 anticorps (APC)

Épitope: AA 1-226

Fonction: Anti-CDK5 Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CDK5 recombinant protein (Position: M1-Q226).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CDK5

Antigène: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Autre désignation: CDK5

Sujet:

Background: CDK5, Cyclin-Dependent Kinase5, is also known as PSSALRE. The p34 (CDC2) protein kinase regulates important transitions in the eukaryotic cell cycle.The PSSALRE expression is in all human tissues and cell lines tested.The the CDK5 gene is mapped to chromosome 7q36. Cyclin-dependent kinase-5 is predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau. CDK5 is required for proper development of the mammalian central nervous system. To be activated, CDK5 must associate with its regulatory subunit, p35 (CDK5R1). CDK5 can phosphorylate DARPP32 at threonine-75, converting it into an inhibitor of PKA.

Gene Full Name: cyclin dependent kinase 5

ID gène: 1020

UniProt: Q00535

Pathways: Cycle Cellulaire, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis