DDX58 anticorps (AA 203-925)

N° du produit ABIN7984284

Cet anticorps Lapin Polyclonal détecte spécifiquement DDX58 dans WB, IHC, ELISA et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour DDX58 anticorps (AA 203-925) (ABIN7984284)

Antigène: DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX58 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Détail du produit anti-DDX58 anticorps

Épitope: AA 203-925

Fonction: Anti-DDX58/RIG-1 Antibody

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human RIGI shares 78.2% amino acid (aa) sequence identity with mouse RIGI.

Attributs du produit: Anti-DDX58/RIG-1 Antibody. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human DDX58/RIG-1 recombinant protein (Position: K203-K925). Human RIGI shares 78.2% amino acid (aa) sequence identity with mouse RIGI.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur DDX58

Antigène: DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Autre désignation: RIGI

Sujet:

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2.

Gene Full Name: RNA sensor RIG-I

Poids moléculaire: 101 kDa

ID gène: 23586

UniProt: O95786

Pathways: Activation of Innate immune Response, Hepatitis C