Desmin anticorps (AA 1-304) (HRP)
Aperçu rapide pour Desmin anticorps (AA 1-304) (HRP) (ABIN7984937)
Antigène
Voir toutes Desmin (DES) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-304
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Fonction
- Anti-Desmin Antibody HRP Conjugated
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- Human Desmin shares 97% amino acid (aa) sequence identity with both mouse,rat Desmin.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human Desmin recombinant protein (Position: M1-T304). Human Desmin shares 97% amino acid (aa) sequence identity with both mouse and rat Desmin.
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Isotype
- IgG
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Indications d'application
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- Desmin (DES)
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Autre désignation
- DES
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Sujet
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Background: DES, also called desmin, is a protein that in humans is encoded by the DES gene, and this gene is mapped to 2q35. DES is the muscle-specific member of the intermediate filament (IF) protein family. It is one of the earliest myogenic markers, both in heart and somites, and is expressed in satellite stem cells and replicating myoblasts. DES is very important in muscle cell architecture and structure since it connects many components of the cytoplasm. It may be also play an important role in mitochondria function. What's more, DES provides attachments between the terminal Z disc and membrane-associated proteins to form a force-transmitting system that parallels the thin filaments at myotendinous junctions.
Gene Full Name: desmin
Sequence Similarities: Belongs to the intermediate filament family.
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ID gène
- 1674
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UniProt
- P17661
Antigène
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