Desmoglein 2 anticorps (AA 24-1020) (PE)

N° du produit ABIN7984996

L’anticorps anti-Desmoglein 2 Monoclonal Souris est utilisé pour la détection de Desmoglein 2 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour Desmoglein 2 anticorps (AA 24-1020) (PE) (ABIN7984996)

Antigène: Desmoglein 2 (DSG2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmoglein 2 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: 2B4D1

Détail du produit anti-Desmoglein 2 anticorps (PE)

Épitope: AA 24-1020

Fonction: Anti-Desmoglein 2/DSG2 Antibody (monoclonal, 2B4D1) PE Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Desmoglein 2/DSG2 recombinant protein (Position: L24-E1020).

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Desmoglein 2

Antigène: Desmoglein 2 (DSG2)

Autre désignation: DSG2

Sujet:

Background: Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in DSG2 display a high degree of penetrance. Disease expression was of variable severity with LV involvement a prominent feature. The low prevalence of classical ECG changes highlights the need to expand current diagnostic criteria to take account of LV disease, childhood disease expression, and incomplete penetrance.

Gene Full Name: desmoglein 2

ID gène: 1829

UniProt: Q14126

Pathways: Cell-Cell Junction Organization