DBT anticorps (AA 46-462) (Fluoro550)

N° du produit ABIN7985271

Cet anticorps Lapin Polyclonal détecte spécifiquement DBT dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DBT anticorps (AA 46-462) (Fluoro550) (ABIN7985271)

Antigène: DBT (Dihydrolipoamide Branched Chain Transacylase E2 (DBT))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DBT est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-DBT anticorps (Fluoro550)

Épitope: AA 46-462

Fonction: Anti-DBT Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human DBT shares 89.7% amino acid (aa) sequence identity with mouse DBT.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human DBT recombinant protein (Position: K46-R462). Human DBT shares 89.7% amino acid (aa) sequence identity with mouse DBT.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur DBT

Antigène: DBT (Dihydrolipoamide Branched Chain Transacylase E2 (DBT))

Autre désignation: DBT

Sujet:

Background: The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene Full Name: dihydrolipoamide branched chain transacylase E2

ID gène: 1629

UniProt: P11182