DMAP1 anticorps (AA 54-401) (PE)

N° du produit ABIN7985915

Cet anticorps anti-DMAP1 Polyclonal Lapin conjugué à PE (ABIN7985915) détecte spécifiquement DMAP1 dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DMAP1 anticorps (AA 54-401) (PE) (ABIN7985915)

Antigène: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMAP1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-DMAP1 anticorps (PE)

Épitope: AA 54-401

Fonction: Anti-DMAP1 Antibody PE Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human DMAP1 recombinant protein (Position: H54-A401).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur DMAP1

Antigène: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Autre désignation: DMAP1

Sujet:

Background: DNA methyltransferase 1-associated protein 1 is an enzyme that in humans is encoded by the DMAP1 gene. This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting ly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

Gene Full Name: DNA methyltransferase 1 associated protein 1

ID gène: 55929

UniProt: Q9NPF5