DRD3 anticorps (C-Term) (APC)

N° du produit ABIN7986247

L’anticorps anti-DRD3 Polyclonal Lapin est utilisé pour la détection de DRD3 dans des échantillons de Humain, Rat et Souris. Il a été validé pour FACS.

Aperçu rapide pour DRD3 anticorps (C-Term) (APC) (ABIN7986247)

Antigène: DRD3 (Dopamine Receptor D3 (DRD3))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DRD3 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-DRD3 anticorps (APC)

Épitope: C-Term

Fonction: Anti-Dopamine Receptor D3/DRD3 Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related rat,mouse sequences by two amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Dopamine Receptor D3, different from the related rat and mouse sequences by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur DRD3

Antigène: DRD3 (Dopamine Receptor D3 (DRD3))

Autre désignation: DRD3

Sujet:

Background: DRD3 is a dopamine receptor that differs in its pharmacology and signaling system from the D1 and D2 receptors and represents both an autoreceptor and a postsynaptic receptor. DRD3 is localized to limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. The DRD3 gene, which is mapped to chromosome 3, is like the DRD2 gene but unlike most other members of this superfamily and it contains introns, 5 in number. The position of 2 of the introns corresponds to that of introns in DRD2. The D3 receptor appeared to mediate some of the effects of antipsychotic drugs and drugs used in the treatment of Parkinson disease, which were previously though to interact only with D2 receptors.

Gene Full Name: dopamine receptor D3

Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

ID gène: 1814

UniProt: P35462

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity