DRD4 anticorps (AA 57-387) (PE)

N° du produit ABIN7986259

L’anticorps anti-DRD4 Polyclonal Lapin est utilisé pour la détection de DRD4 dans des échantillons de Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour DRD4 anticorps (AA 57-387) (PE) (ABIN7986259)

Antigène: DRD4 (Dopamine Receptor D4 (DRD4))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DRD4 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-DRD4 anticorps (PE)

Épitope: AA 57-387

Fonction: Anti-DRD4 Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse DRD4 recombinant protein (Position: A57-C387).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur DRD4

Antigène: DRD4 (Dopamine Receptor D4 (DRD4))

Autre désignation: Drd4

Sujet:

Background: D (4) dopamine receptor is a protein that in humans is encoded by the Drd4 gene. This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. And this subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: dopamine receptor D4

ID gène: 13491

UniProt: P51436

Pathways: cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity