Dysferlin anticorps (AA 51-747) (Fluoro647)

N° du produit ABIN7986677

Cet anticorps anti-Dysferlin Polyclonal Lapin conjugué à Fluoro647 (ABIN7986677) détecte spécifiquement Dysferlin dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Dysferlin anticorps (AA 51-747) (Fluoro647) (ABIN7986677)

Antigène: Dysferlin (DYSF)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dysferlin est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-Dysferlin anticorps (Fluoro647)

Épitope: AA 51-747

Fonction: Anti-Dysferlin/DYSF Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human DYSF recombinant protein (Position: E51-H747).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Dysferlin

Antigène: Dysferlin (DYSF)

Autre désignation: DYSF

Sujet:

Background: Dysferlin also known as dystrophy-associated fer-1-like protein is a protein that in humans is encoded by the DYSF gene. The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants.

Gene Full Name: dysferlin

ID gène: 8291

UniProt: O75923