Dystrophin anticorps (AA 3076-3404) (PE)

N° du produit ABIN7986731

Cet anticorps anti-Dystrophin Polyclonal Lapin conjugué à PE (ABIN7986731) détecte spécifiquement Dystrophin dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Dystrophin anticorps (AA 3076-3404) (PE) (ABIN7986731)

Antigène: Dystrophin (DMD)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dystrophin est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-Dystrophin anticorps (PE)

Épitope: AA 3076-3404

Fonction: Anti-Dystrophin/DMD Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human Dystrophin shares 100% amino acid (aa) sequence identity with mouse Dystrophin.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Dystrophin recombinant protein (Position: H3076-D3404). Human Dystrophin shares 100% amino acid (aa) sequence identity with mouse Dystrophin.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Dystrophin

Antigène: Dystrophin (DMD)

Autre désignation: DMD

Sujet:

Background: Dystrophin, also known as DMD, is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane. It is mapped to Xp21.2-p21.1. This complex is variously known as the costamere or thedystrophin-associated protein complex. Many muscle proteins, such as α-dystrobrevin, syncoilin, synemin, sarcoglycan, dystroglycan, and sarcospan, colocalize with dystrophin at the costamere. Dystrophin is a protein located between the sarcolemma and the outermost layer of myofilaments in the muscle fiber (myofiber). It is a cohesive protein, linking actin filaments to another support protein that resides on the inside surface of each muscle fiber's plasma membrane (sarcolemma).

Gene Full Name: dystrophin

Sequence Similarities: Contains 2 CH (calponin-homology) domains.

ID gène: 1756

UniProt: P11532

Pathways: Skeletal Muscle Fiber Development