DKK3 anticorps (AA 31-130) (Cy5)
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- Antigène Voir toutes DKK3 Anticorps
- DKK3
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Épitope
- AA 31-130
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Reactivité
- Souris, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DKK3 est conjugé à/à la Cy5
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Souris, Lapin
- Homologie
- Human,Rat,Cow,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human DKK3
- Isotype
- IgG
- Top Product
- Discover our top product DKK3 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- DKK3
- Abstract
- DKK3 Produits
- Synonymes
- anticorps REIC, anticorps RIG, anticorps reic, anticorps dkk-3, anticorps AW061014, anticorps C87148, anticorps Reic, anticorps p29, anticorps dickkopf WNT signaling pathway inhibitor 3, anticorps dickkopf WNT signaling pathway inhibitor 3 S homeolog, anticorps DKK3, anticorps dkk3, anticorps dkk3.S, anticorps Dkk3
- Sujet
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Synonyms: RIG, REIC, Dickkopf-related protein 3, Dickkopf-3, Dkk-3, hDkk-3, DKK3, UNQ258/PRO295
Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
- ID gène
- 27122
- UniProt
- Q9UBP4
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