EXOSC2 anticorps (AA 62-293) (Fluoro647)

N° du produit ABIN7989340

L’anticorps anti-EXOSC2 Polyclonal Lapin est utilisé pour la détection de EXOSC2 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour EXOSC2 anticorps (AA 62-293) (Fluoro647) (ABIN7989340)

Antigène: EXOSC2 (Exosome Component 2 (EXOSC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EXOSC2 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-EXOSC2 anticorps (Fluoro647)

Épitope: AA 62-293

Fonction: Anti-RRP4/EXOSC2 Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human RRP4/EXOSC2 recombinant protein (Position: R62-G293).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur EXOSC2

Antigène: EXOSC2 (Exosome Component 2 (EXOSC2))

Autre désignation: EXOSC2

Sujet:

Background: Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snoRNA and snRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. EXOSC2 is a non-catalytic component of the RNA exosome complex that has 3'->5' exoribonuclease activity and involves in a multitude of cellular RNA processing and degradation events.

Gene Full Name: exosome component 2

ID gène: 23404

UniProt: Q13868

Pathways: SARS-CoV-2 Protein Interactome