EXOSC2 anticorps (AA 62-293)

N° du produit ABIN7989341

Cet anticorps anti-EXOSC2 Polyclonal Lapin (ABIN7989341) détecte spécifiquement EXOSC2 dans WB, IHC, ELISA et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour EXOSC2 anticorps (AA 62-293) (ABIN7989341)

Antigène: EXOSC2 (Exosome Component 2 (EXOSC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EXOSC2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Détail du produit anti-EXOSC2 anticorps

Épitope: AA 62-293

Fonction: Anti-RRP4/EXOSC2 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-RRP4/EXOSC2 Antibody. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human RRP4/EXOSC2 recombinant protein (Position: R62-G293).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur EXOSC2

Antigène: EXOSC2 (Exosome Component 2 (EXOSC2))

Autre désignation: EXOSC2

Sujet:

Background: Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snoRNA and snRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. EXOSC2 is a non-catalytic component of the RNA exosome complex that has 3'->5' exoribonuclease activity and involves in a multitude of cellular RNA processing and degradation events.

Gene Full Name: exosome component 2

Poids moléculaire: 33 kDa

ID gène: 23404

UniProt: Q13868

Pathways: SARS-CoV-2 Protein Interactome