FANCA anticorps (AA 1272-1439) (Fluoro488)

N° du produit ABIN7989620

Cet anticorps anti-FANCA Polyclonal Lapin conjugué à Fluoro488 (ABIN7989620) détecte spécifiquement FANCA dans FACS. L’anticorps est réactif avec des échantillons de Rat et Souris.

Aperçu rapide pour FANCA anticorps (AA 1272-1439) (Fluoro488) (ABIN7989620)

Antigène: FANCA (Fanconi Anemia Group A Protein (FANCA))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCA est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-FANCA anticorps (Fluoro488)

Épitope: AA 1272-1439

Fonction: Anti-Fanca/FAA Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Fanca/FAA recombinant protein (Position: E1272-F1439).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur FANCA

Antigène: FANCA (Fanconi Anemia Group A Protein (FANCA))

Autre désignation: Fanca

Sujet:

Background: Fanconi anaemia, complementation group A, also known as FAA, FACA and FANCA, is a protein which in humans is encoded by the FANCA gene. Acts upstream of or within several processes, including gonad development, regulation of CD40 signaling pathway, and regulation of regulatory T cell differentiation. Predicted to be located in nucleoplasm. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed in several structures, including gut, liver, lung, reproductive system, and spleen. Used to study Fanconi anemia complementation group A. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia (multiple), acute myeloid leukemia, esophagus squamous cell carcinoma, ovarian disease (multiple), and skin melanoma. Orthologous to human FANCA (FA complementation group A).

Gene Full Name: Fanconi anemia, complementation group A

ID gène: 14087

UniProt: Q9JL70

Pathways: Réparation de l'ADN