Fibrinogen beta Chain anticorps (Middle Region) (APC)
Aperçu rapide pour Fibrinogen beta Chain anticorps (Middle Region) (APC) (ABIN7990330)
Antigène
Voir toutes Fibrinogen beta Chain (FGB) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- Anti-Fibrinogen beta chain/FGB Antibody APC Conjugated
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Homologie
- different from the related mouse sequence by three amino acids,and from the related rat sequence by five amino acids.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence in the middle region of human FGB, different from the related mouse sequence by three amino acids, and from the related rat sequence by five amino acids.
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Isotype
- IgG
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Indications d'application
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Date de péremption
- 12 months
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- Fibrinogen beta Chain (FGB)
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Autre désignation
- FGB
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Sujet
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Background: Fibrinogen beta chain, mapped to 4q31.3, is also known as FGB. The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: fibrinogen beta chain
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ID gène
- 2244
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UniProt
- P02675
Antigène
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