FOXP3 anticorps (AA 101-431)

N° du produit ABIN7991622

Cet anticorps Lapin Polyclonal détecte spécifiquement FOXP3 dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour FOXP3 anticorps (AA 101-431) (ABIN7991622)

Antigène: FOXP3 (Forkhead Box P3 (FOXP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXP3 est non-conjugé

Application: Immunohistochemistry (IHC)

Classe de qualité: Carrier-free

Détail du produit anti-FOXP3 anticorps

Épitope: AA 101-431

Fonction: Anti-Forkhead box protein P3 FOXP3 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human FOXP3 shares 88% amino acid (aa) sequence identity with mouse FOXP3.

Attributs du produit: Anti-Forkhead box protein P3 FOXP3 Antibody. Tested in IHC applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human FOXP3 recombinant protein (Position: H101-P431). Human FOXP3 shares 88% amino acid (aa) sequence identity with mouse FOXP3.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FOXP3

Antigène: FOXP3 (Forkhead Box P3 (FOXP3))

Autre désignation: FOXP3

Sujet:

Background: FOXP3 (forkhead box P3) is a protein involved in immune system responses. The human FOXP3 genes contain 11 coding exons. Exon-intron boundaries are identical across the coding regions of the mouse and human genes. By genomic sequence analysis, the FOXP3 gene maps to the p arm of the X chromosome (specifically, Xp11.23). A member of the FOX protein family, FOXP3 appears to function as a master regulator in the development and function of regulatory T cells. While the precise control mechanism has not yet been established, FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription.

Gene Full Name: forkhead box P3

Sequence Similarities: Contains 1 C2H2-type zinc finger.

ID gène: 50943

UniProt: Q9BZS1

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation