GGCX anticorps (AA 75-730) (Fluoro488)

N° du produit ABIN7992554

Cet anticorps anti-GGCX Polyclonal Lapin conjugué à Fluoro488 (ABIN7992554) détecte spécifiquement GGCX dans FACS. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour GGCX anticorps (AA 75-730) (Fluoro488) (ABIN7992554)

Antigène: GGCX (gamma-Glutamyl Carboxylase (GGCX))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GGCX est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-GGCX anticorps (Fluoro488)

Épitope: AA 75-730

Fonction: Anti-GGCX Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GGCX recombinant protein (Position: M75-A730).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur GGCX

Antigène: GGCX (gamma-Glutamyl Carboxylase (GGCX))

Autre désignation: GGCX

Sujet:

Background: Gamma-glutamyl carboxylase is an enzyme that in humans is encoded by the GGCX gene, located on chromosome 2 at 2p12. This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants.

Gene Full Name: gamma-glutamyl carboxylase

ID gène: 2677

UniProt: P38435

Pathways: SARS-CoV-2 Protein Interactome