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GRIA4 anticorps (AA 176-350)

L’anticorps anti-GRIA4 Polyclonal Lapin est utilisé pour la détection de GRIA4 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et FACS.
N° du produit ABIN7993729
500,50 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 8 à 12 jours ouvrables

Aperçu rapide pour GRIA4 anticorps (AA 176-350) (ABIN7993729)

Antigène

Voir toutes GRIA4 Anticorps
GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Reactivité

  • 81
  • 67
  • 44
  • 2
  • 2
  • 2
Humain, Souris, Rat

Hôte

  • 83
  • 2
Lapin

Clonalité

  • 73
  • 12
Polyclonal

Conjugué

  • 35
  • 7
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp GRIA4 est non-conjugé

Application

  • 65
  • 28
  • 27
  • 19
  • 13
  • 13
  • 8
  • 6
  • 4
  • 3
  • 3
  • 2
Western Blotting (WB), Flow Cytometry (FACS)

Classe de qualité

Carrier-free
  • Épitope

    • 15
    • 11
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 176-350

    Fonction

    Anti-Ionotropic Glutamate receptor 4/GRIA4 Antibody

    Specificité

    No cross reactivity with other proteins.

    Réactivité croisée (Details)

    No cross-reactivity with other proteins

    Homologie

    Human GRIA4 shares 99% amino acid (aa) sequence identity with both mouse,rat GRIA4.

    Attributs du produit

    Anti-Ionotropic Glutamate receptor 4/GRIA4 Antibody. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived human GRIA4 recombinant protein (Position: Q176-K350). Human GRIA4 shares 99% amino acid (aa) sequence identity with both mouse and rat GRIA4.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    Date de péremption

    12 months
  • Antigène

    GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

    Autre désignation

    GRIA4

    Sujet

    Background: Glutamate receptor 4 also named GRIA4 or GLUR4, is a protein that in humans is encoded by the GRIA4 gene. It is mapped to 11q22.3. This gene is a member of a family of L-glutamate-gated ion channels that mediate fast synaptic excitatory neurotransmission. These channels are also responsive to the glutamate agonist, alpha-amino-3-hydroxy-5-methyl-4-isoxazolpropionate (AMPA). Some haplotypes of this gene show a positive association with schizophrenia. What's more, glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels.

    Gene Full Name: glutamate ionotropic receptor AMPA type subunit 4

    Poids moléculaire

    101 kDa

    ID gène

    2893

    UniProt

    P48058

    Pathways

    Signalisation PI3K-Akt
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