GSTM2 anticorps (Middle Region) (FITC)

N° du produit ABIN7994343

Cet anticorps Lapin Polyclonal détecte spécifiquement GSTM2 dans FACS. Il présente une réactivité avec des échantillons de Rat et Souris.

Aperçu rapide pour GSTM2 anticorps (Middle Region) (FITC) (ABIN7994343)

Antigène: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM2 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-GSTM2 anticorps (FITC)

Épitope: Middle Region

Fonction: Anti-GSTM2 Antibody FITC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human GSTM2 shares 95.5% amino acid (aa) sequence identity with rat GSTM2.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of mouse GSTM2. Human GSTM2 shares 95.5% amino acid (aa) sequence identity with rat GSTM2.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur GSTM2

Antigène: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Autre désignation: GSTM2

Sujet:

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Gene Full Name: glutathione S-transferase, mu 2

ID gène: 14863

UniProt: P15626

Pathways: Negative Regulation of Transporter Activity