GLDC anticorps (AA 574-1020) (HRP)

N° du produit ABIN7994553

Cet anticorps Souris Monoclonal détecte spécifiquement GLDC dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GLDC anticorps (AA 574-1020) (HRP) (ABIN7994553)

Antigène: GLDC (Glycine Dehydrogenase (GLDC))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GLDC est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 3D3D3

Détail du produit anti-GLDC anticorps (HRP)

Épitope: AA 574-1020

Fonction: Anti-Glycine decarboxylase/GLDC Antibody (monoclonal, 3D3D3) HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Glycine decarboxylase/GLDC recombinant protein (Position: K574-S1020).

Isotype: IgG1

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GLDC

Antigène: GLDC (Glycine Dehydrogenase (GLDC))

Autre désignation: GLDC

Sujet:

Background: Glycine decarboxylase also known as glycine cleavage system P protein or glycine dehydrogenase is an enzyme that in humans is encoded by the GLDC gene. Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).

Gene Full Name: glycine decarboxylase

ID gène: 2731

UniProt: P23378