GLDC anticorps (AA 574-1020)

N° du produit ABIN7994557

L’anticorps anti-GLDC Monoclonal Souris est utilisé pour la détection de GLDC dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et IHC.

Aperçu rapide pour GLDC anticorps (AA 574-1020) (ABIN7994557)

Antigène: GLDC (Glycine Dehydrogenase (GLDC))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GLDC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Classe de qualité: Carrier-free

Clone: 3D3D3

Détail du produit anti-GLDC anticorps

Épitope: AA 574-1020

Fonction: Anti-Glycine decarboxylase/GLDC Antibody (monoclonal, 3D3D3)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Glycine decarboxylase/GLDC Antibody.(monoclonal, 3D3D3). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Glycine decarboxylase/GLDC recombinant protein (Position: K574-S1020).

Isotype: IgG1

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GLDC

Antigène: GLDC (Glycine Dehydrogenase (GLDC))

Autre désignation: GLDC

Sujet:

Background: Glycine decarboxylase also known as glycine cleavage system P protein or glycine dehydrogenase is an enzyme that in humans is encoded by the GLDC gene. Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).

Gene Full Name: glycine decarboxylase

Poids moléculaire: 113 kDa

ID gène: 2731

UniProt: P23378