GHITM anticorps (AA 1-345) (Biotin)

N° du produit ABIN7995482

Cet anticorps anti-GHITM Polyclonal Lapin conjugué à Biotin (ABIN7995482) détecte spécifiquement GHITM dans ELISA, WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GHITM anticorps (AA 1-345) (Biotin) (ABIN7995482)

Antigène: GHITM (Growth Hormone Inducible Transmembrane Protein (GHITM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GHITM est conjugé à/à la Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GHITM anticorps (Biotin)

Épitope: AA 1-345

Fonction: Anti-GHITM Antibody Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GHITM recombinant protein (Position: M1-K345).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GHITM

Antigène: GHITM (Growth Hormone Inducible Transmembrane Protein (GHITM))

Autre désignation: GHITM

Sujet:

Background: Growth hormone-inducible transmembrane protein (GHITM), also known as transmembrane BAX inhibitor motif containing protein 5 (TMBIM5), is a protein that in humans is encoded by the GHITM gene on chromosome 10. GHITM, also known asMICS1, TMBIM5 orDERP2, is a mitochondrial protein which localizes in the inner membrane.GHITM is involved in mitochondrial morphology in specific cristae structures and the apoptotic release of cytochrome c from the mitochondria. The gene of GHITM maps to chromosome 10q23.1, and encodes a 345-amino-acid protein with a calculated molecular mass of 37 kDa. The apparent molecular weight has been reported to be 42 kDa, the increased size in the protein may be due to post-translational modifications. GHITM can be cleaved into smaller forms of 23-27 kDa.

Gene Full Name: growth hormone inducible transmembrane protein

ID gène: 27069

UniProt: Q9H3K2

Pathways: SARS-CoV-2 Protein Interactome