GCH1 anticorps (AA 1-250) (FITC)

N° du produit ABIN7995564

Cet anticorps Lapin Polyclonal détecte spécifiquement GCH1 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GCH1 anticorps (AA 1-250) (FITC) (ABIN7995564)

Antigène: GCH1 (GTP Cyclohydrolase 1 (GCH1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCH1 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-GCH1 anticorps (FITC)

Épitope: AA 1-250

Fonction: Anti-GCH1 Antibody FITC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human GCH1 shares 89.2%,92.5% amino acid (aa) sequence identity with mouse,rat GCH1,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GCH1 recombinant protein (Position: M1-S250). Human GCH1 shares 89.2% and 92.5% amino acid (aa) sequence identity with mouse and rat GCH1, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur GCH1

Antigène: GCH1 (GTP Cyclohydrolase 1 (GCH1))

Autre désignation: GCH1

Sujet:

Background: This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme.

Gene Full Name: GTP cyclohydrolase 1

ID gène: 2643

UniProt: P30793