HNF1A anticorps (AA 431-631) (Biotin)

N° du produit ABIN7997982

Cet anticorps Lapin Polyclonal détecte spécifiquement HNF1A dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour HNF1A anticorps (AA 431-631) (Biotin) (ABIN7997982)

Antigène: HNF1A (HNF1 Homeobox A (HNF1A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNF1A est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-HNF1A anticorps (Biotin)

Épitope: AA 431-631

Fonction: Anti-HNF1/HNF1A Antibody Biotin Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human HNF1 shares 93%,92% amino acid (aa) sequences identity with mouse,rat HNF1,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human HNF1 recombinant protein (Position: A431-Q631). Human HNF1 shares 93% and 92% amino acid (aa) sequences identity with mouse and rat HNF1, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur HNF1A

Antigène: HNF1A (HNF1 Homeobox A (HNF1A))

Autre désignation: HNF1A

Sujet:

Background: HNF1 homeobox A (hepatocyte nuclear factor 1 homeobox A), also known as HNF1A or TCF1, is a human gene. It is mapped to chromosome 12q24.3. The protein encoded by this gene is a transcription factor that is highly expressed in the liver and is involved in the regulation of the expression of several liver-specific genes. HNF1A can function as a dimer. What's more, deletion of the HNF1A activation domains or interruption of the HNF1-binding sites in the LCT promoter resulted in complete loss of transcriptional activity.

Gene Full Name: HNF1 homeobox A

Sequence Similarities: Belongs to the HNF1 homeobox family.

ID gène: 6927

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis