HYAL1 anticorps (N-Term) (Cy3)

N° du produit ABIN7998511

L’anticorps anti-HYAL1 Polyclonal Lapin est utilisé pour la détection de HYAL1 dans des échantillons de Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour HYAL1 anticorps (N-Term) (Cy3) (ABIN7998511)

Antigène: HYAL1 (Hyaluronidase-1 (HYAL1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HYAL1 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-HYAL1 anticorps (Cy3)

Épitope: N-Term

Fonction: Anti-HYAL1 Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of mouse HYAL1, which shares 72.7% and 95.5% amino acid (aa) sequence identity with human and rat HYAL1, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur HYAL1

Antigène: HYAL1 (Hyaluronidase-1 (HYAL1))

Autre désignation: Hyal1

Sujet:

Background: Hyaluronidase-1, also known as HYAL1 or LUCA1, is an enzyme that in humans is encoded by the HYAL1 gene. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.

Gene Full Name: hyaluronoglucosaminidase 1

ID gène: 15586

UniProt: Q91ZJ9

Pathways: Glycosaminoglycan Metabolic Process