IMPDH2 anticorps (Middle Region)
Aperçu rapide pour IMPDH2 anticorps (Middle Region) (ABIN7999257)
Antigène
Voir toutes IMPDH2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- Middle Region
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Fonction
- Anti-IMPDH2 Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Homologie
- identical to the related mouse,rat sequences.
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Attributs du produit
- Anti-IMPDH2 Antibody. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence in the middle region of human IMPDH2, identical to the related mouse and rat sequences.s
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL/mL, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/mL/1x10^6 cells, Human
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
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Autre désignation
- IMPDH2
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Sujet
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Background: Inosine-5'-monophosphate dehydrogenase 2, also known as IMP dehydrogenase 2, is an enzyme that in humans is encoded by the IMPDH2 gene. This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Gene Full Name: inosine monophosphate dehydrogenase 2
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Poids moléculaire
- 56 kDa
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ID gène
- 3615
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UniProt
- P12268
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Pathways
- Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome
Antigène
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