IRF5 anticorps (C-Term) (Fluoro488)

N° du produit ABIN8001267

L’anticorps anti-IRF5 Polyclonal Lapin est utilisé pour la détection de IRF5 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour IRF5 anticorps (C-Term) (Fluoro488) (ABIN8001267)

Antigène: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF5 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-IRF5 anticorps (Fluoro488)

Épitope: C-Term

Fonction: Anti-IRF5 Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by three amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human IRF5, different from the related mouse sequence by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur IRF5

Antigène: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Autre désignation: IRF5

Sujet:

Background: Interferon regulatory factor 5, also called IRF5 or SLEB10, is a protein that in humans is encoded by the IRF5 gene. IRF5 gene is mapped to 7q32.1. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. This gene is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection.

Gene Full Name: interferon regulatory factor 5

Sequence Similarities: Contains 1 HMG box DNA-binding domain.

ID gène: 3663

UniProt: Q13568

Pathways: Signalisation TLR, Autophagy