IRF5 anticorps (AA 98-477) (Biotin)

N° du produit ABIN8001276

L’anticorps anti-IRF5 Polyclonal Lapin est utilisé pour la détection de IRF5 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour IRF5 anticorps (AA 98-477) (Biotin) (ABIN8001276)

Antigène: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF5 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-IRF5 anticorps (Biotin)

Épitope: AA 98-477

Fonction: Anti-IRF5 Antibody Biotin Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human IRF5 shares 85.6% amino acid (aa) sequence identity with mouse IRF5.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human IRF5 recombinant protein (Position: R98-A477). Human IRF5 shares 85.6% amino acid (aa) sequence identity with mouse IRF5.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur IRF5

Antigène: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Autre désignation: IRF5

Sujet:

Background: Interferon regulatory factor 5, also called IRF5 or SLEB10, is a protein that in humans is encoded by the IRF5 gene. IRF5 gene is mapped to 7q32.1. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. This gene is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection.

Gene Full Name: interferon regulatory factor 5

ID gène: 3663

UniProt: Q13568

Pathways: Signalisation TLR, Autophagy