IL12B anticorps (AA 23-321) (Fluoro488)

N° du produit ABIN8001806

Cet anticorps Lapin Polyclonal détecte spécifiquement IL12B dans FACS. Il présente une réactivité avec des échantillons de Rat.

Aperçu rapide pour IL12B anticorps (AA 23-321) (Fluoro488) (ABIN8001806)

Antigène: IL12B (Interleukin 12 beta (IL12B))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL12B est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-IL12B anticorps (Fluoro488)

Épitope: AA 23-321

Fonction: Anti-IL12 p40/IL12B Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived rat IL-12 (p40) recombinant protein (Position: M23-S321).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur IL12B

Antigène: IL12B (Interleukin 12 beta (IL12B))

Autre désignation: IL12B

Sujet:

Background: Subunit beta of interleukin 12, also known as interleukin 12B, or IL12B, is a subunit of human interleukin 12. It is mapped to 5q33.3. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease.

Gene Full Name: interleukin 12B

Sequence Similarities: Belongs to the type I cytokine receptor family. Type 3 subfamily.

ID gène: 64546

UniProt: Q9R278

Pathways: Signalistation JAK/STAT, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation