IL-13 anticorps (AA 36-146) (Cy3)

N° du produit ABIN8001849

L’anticorps anti-IL-13 Polyclonal Lapin est utilisé pour la détection de IL-13 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour IL-13 anticorps (AA 36-146) (Cy3) (ABIN8001849)

Antigène: IL-13 (IL13) (Interleukin 13 (IL13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-13 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-IL-13 anticorps (Cy3)

Épitope: AA 36-146

Fonction: Anti-IL13 Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: coli-derived human IL13 recombinant protein (Position: P36-N146). Human IL13 shares 55.3%,61.9% amino acid (aa) sequence identity with mouse,rat IL13,respectively.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human IL13 recombinant protein (Position: P36-N146). Human IL13 shares 55.3% and 61.9% amino acid (aa) sequence identity with mouse and rat IL13, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur IL-13

Antigène: IL-13 (IL13) (Interleukin 13 (IL13))

Autre désignation: IL13

Sujet:

Background: Interleukin 13 is a protein that in humans is encoded by the IL-13 gene. It is a kind of cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, which is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. Furthermore, this gene acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.

Gene Full Name: interleukin 13

ID gène: 3596

UniProt: P35225

Pathways: Signalistation JAK/STAT, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport