IL2 Receptor beta anticorps (C-Term) (Fluoro647)

N° du produit ABIN8002264

Cet anticorps anti-IL2 Receptor beta Polyclonal Lapin conjugué à Fluoro647 (ABIN8002264) détecte spécifiquement IL2 Receptor beta dans FACS. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour IL2 Receptor beta anticorps (C-Term) (Fluoro647) (ABIN8002264)

Antigène: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL2 Receptor beta est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-IL2 Receptor beta anticorps (Fluoro647)

Épitope: C-Term

Fonction: Anti-IL2 Receptor beta/IL2RB Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related human sequence by sixteen amino acids,and from the related rat sequence by fourteen amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of mouse IL2RB, different from the related human sequence by sixteen amino acids, and from the related rat sequence by fourteen amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur IL2 Receptor beta

Antigène: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Autre désignation: Il2rb

Sujet:

Background: IL2RB (INTERLEUKIN 2 RECEPTOR, BETA), also called CD122, is a protein that in humans is encoded by the IL2RB gene. The gene represents the beta subunit and is a type I membrane protein. IL2RB is mapped to 22q12.3. The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10. The IL2 receptor is present in 3 forms with respect to binding ability to IL2: high, intermediate, and low affinity forms. Analysis of mutants of the beta chain of the IL2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic domains, showing that the signaling pathways responsible for these unique developmental outcomes are separable.

Gene Full Name: interleukin 2 receptor, beta chain

ID gène: 16185

UniProt: P16297

Pathways: Signalistation JAK/STAT, Growth Factor Binding