IL2 Receptor beta anticorps (AA 268-551) (Fluoro647)

N° du produit ABIN8002275

L’anticorps anti-IL2 Receptor beta Polyclonal Lapin est utilisé pour la détection de IL2 Receptor beta dans des échantillons de Souris, Humain et Rat. Il a été validé pour FACS.

Aperçu rapide pour IL2 Receptor beta anticorps (AA 268-551) (Fluoro647) (ABIN8002275)

Antigène: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reactivité: Souris, Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL2 Receptor beta est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-IL2 Receptor beta anticorps (Fluoro647)

Épitope: AA 268-551

Fonction: Anti-IL2 Receptor beta/p75/IL2RB Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human IL2 Receptor beta/p75/IL2RB recombinant protein (Position: R268-V551).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur IL2 Receptor beta

Antigène: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Autre désignation: IL2RB

Sujet:

Background: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an upstream long terminal repeat (LTR) results in placenta-specific expression.

Gene Full Name: interleukin 2 receptor subunit beta

ID gène: 3560

UniProt: P14784

Pathways: Signalistation JAK/STAT, Growth Factor Binding