IL-7 anticorps (AA 26-154) (Cy3)

N° du produit ABIN8002817

Cet anticorps Lapin Polyclonal détecte spécifiquement IL-7 dans FACS. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour IL-7 anticorps (AA 26-154) (Cy3) (ABIN8002817)

Antigène: IL-7 (IL7) (Interleukin 7 (IL7))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-7 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-IL-7 anticorps (Cy3)

Épitope: AA 26-154

Fonction: Anti-IL7 Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: coli-derived mouse IL7 recombinant protein (Position: E26-I154). Mouse IL7 shares 56.4%,87.6% amino acid (aa) sequence identity with human,rat IL7,respectively.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived mouse IL7 recombinant protein (Position: E26-I154). Mouse IL7 shares 56.4% and 87.6% amino acid (aa) sequence identity with human and rat IL7, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur IL-7

Antigène: IL-7 (IL7) (Interleukin 7 (IL7))

Autre désignation: Il7

Sujet:

Background: Interleukin 7  (IL-7) is a protein that in humans is encoded by the IL7 gene. The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. And it is found to be a cofactor for V (D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. In addition, this cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.

Gene Full Name: interleukin 7

ID gène: 16196

UniProt: P10168

Pathways: Signalistation JAK/STAT