IL7R anticorps (AA 33-433) (Fluoro550)

N° du produit ABIN8002863

L’anticorps anti-IL7R Polyclonal Lapin est utilisé pour la détection de IL7R dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour IL7R anticorps (AA 33-433) (Fluoro550) (ABIN8002863)

Antigène: IL7R (Interleukin 7 Receptor (IL7R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL7R est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-IL7R anticorps (Fluoro550)

Épitope: AA 33-433

Fonction: Anti-CD127/IL7R Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human IL7R shares 63.1% amino acid (aa) sequence identity with mouse IL7R.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CD127/IL7R recombinant protein (Position: A33-Q433). Human IL7R shares 63.1% amino acid (aa) sequence identity with mouse IL7R.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur IL7R

Antigène: IL7R (Interleukin 7 Receptor (IL7R))

Autre désignation: IL7R

Sujet:

Background: The interleukin-7 receptor, also known as IL7R alpha, is a protein found on the surface of cells. It is mapped to 5p13. Interleukin-7 receptor has been shown to play a critical role in the development of immune cells called lymphocytes - specifically in a process known as V(D)J recombination. This protein is also found to control the accessibility of a region of the genome that contains the T-cell receptor gamma gene, by STAT5 and histone acetylation. Knockout studies in mice suggest that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. Functional defects in this protein may be associated with the pathogenesis of severe combined immunodeficiency (SCID).

Gene Full Name: interleukin 7 receptor

ID gène: 3575

UniProt: P16871

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size