IRAK2 anticorps (C-Term) (Fluoro647)

N° du produit ABIN8002957

Cet anticorps anti-IRAK2 Polyclonal Lapin conjugué à Fluoro647 (ABIN8002957) détecte spécifiquement IRAK2 dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IRAK2 anticorps (C-Term) (Fluoro647) (ABIN8002957)

Antigène: IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRAK2 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-IRAK2 anticorps (Fluoro647)

Épitope: C-Term

Fonction: Anti-IRAK2 Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related rat sequence by one amino acid,and from the related mouse sequence by three amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human IRAK2, different from the related rat sequence by one amino acid, and from the related mouse sequence by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur IRAK2

Antigène: IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))

Autre désignation: IRAK2

Sujet:

Background: Interleukin-1 receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene. This gene is mapped to 3p25.3. IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. It binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.

Gene Full Name: interleukin 1 receptor associated kinase 2

Sequence Similarities: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.

ID gène: 3656

UniProt: O43187

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades