JAG2 anticorps (AA 22-1153) (Fluoro488)

N° du produit ABIN8003577

L’anticorps anti-JAG2 Polyclonal Lapin est utilisé pour la détection de JAG2 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour JAG2 anticorps (AA 22-1153) (Fluoro488) (ABIN8003577)

Antigène: JAG2 (Jagged 2 (JAG2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JAG2 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-JAG2 anticorps (Fluoro488)

Épitope: AA 22-1153

Fonction: Anti-Jagged 2/JAG2 Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human JAG2 shares 91.1%,91% amino acid (aa) sequence identity with mouse,rat JAG2,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Jagged 2/JAG2 recombinant protein (Position: Q22-N1153). Human JAG2 shares 91.1% and 91% amino acid (aa) sequence identity with mouse and rat JAG2, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur JAG2

Antigène: JAG2 (Jagged 2 (JAG2))

Autre désignation: JAG2

Sujet:

Background: Protein jagged-2, also known as SER2, is a protein that in humans is encoded by the JAG2 gene. It is mapped to 14q32.33. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Notch ligands Delta1 and JAG2 are subject to presenilin-dependent, intramembranous gamma-secretase processing, resulting in the production of soluble intracellular derivatives. JAG2 can promote the growth and dissemination of uveal melanoma cells.

Gene Full Name: jagged canonical Notch ligand 2

ID gène: 3714

UniProt: Q9Y219

Pathways: Signalisation Notch, Sensory Perception of Sound