JAG2 anticorps (AA 22-1153)

N° du produit ABIN8003585

Cet anticorps Lapin Polyclonal détecte spécifiquement JAG2 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour JAG2 anticorps (AA 22-1153) (ABIN8003585)

Antigène: JAG2 (Jagged 2 (JAG2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JAG2 est non-conjugé

Application: Western Blotting (WB), ELISA

Classe de qualité: Carrier-free

Détail du produit anti-JAG2 anticorps

Épitope: AA 22-1153

Fonction: Anti-Jagged 2/JAG2 Antibody

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human JAG2 shares 91.1%,91% amino acid (aa) sequence identity with mouse,rat JAG2,respectively.

Attributs du produit: Anti-Jagged 2/JAG2 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Jagged 2/JAG2 recombinant protein (Position: Q22-N1153). Human JAG2 shares 91.1% and 91% amino acid (aa) sequence identity with mouse and rat JAG2, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur JAG2

Antigène: JAG2 (Jagged 2 (JAG2))

Autre désignation: JAG2

Sujet:

Background: Protein jagged-2, also known as SER2, is a protein that in humans is encoded by the JAG2 gene. It is mapped to 14q32.33. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Notch ligands Delta1 and JAG2 are subject to presenilin-dependent, intramembranous gamma-secretase processing, resulting in the production of soluble intracellular derivatives. JAG2 can promote the growth and dissemination of uveal melanoma cells.

Gene Full Name: jagged canonical Notch ligand 2

Poids moléculaire: 130 kDa

ID gène: 3714

UniProt: Q9Y219

Pathways: Signalisation Notch, Sensory Perception of Sound