CYBB anticorps (AA 501-570)

N° du produit ABIN750688

Cet anticorps Lapin Polyclonal détecte spécifiquement CYBB dans WB, ELISA, FACS, IHC (p), IF (cc), IF (p) et IHC (fro). Il présente une réactivité envers Humain, Souris, Rat, Lapin et Poulet et a été mentionné dans 6+ publications.

Aperçu rapide pour CYBB anticorps (AA 501-570) (ABIN750688)

Antigène: CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

Reactivité: Humain, Souris, Rat, Lapin, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYBB est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CYBB anticorps

Épitope: AA 501-570

Réactivité croisée: Poulet, Humain, Souris, Lapin, Rat

Homologie: Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NOX2/gp91phox

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CYBB (ABIN750688)

Ye, Wu, Liu, Chen, Zhang, Lu, Zhou, Li, Zhang, Xia, Zhuang, Hang et al.: "Inhibition of leukotriene B4 synthesis protects against early brain injury possibly via reducing the neutrophil-generated inflammatory response and oxidative stress after subarachnoid hemorrhage in ..." dans: Behavioural brain research, Vol. 339, pp. 19-27, (2017) (PubMed).

Wakatsuki, Furuno, Ohshima, Araki: "Oxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration." dans: The Journal of cell biology, Vol. 211, Issue 4, pp. 881-96, (2015) (PubMed).

Kashiwabara, Ambe, Nakagawa, Watanabe: "Immunohistochemical localization of Nox in mouse circumvallate papillae." dans: Tissue & cell, Vol. 47, Issue 6, pp. 550-8, (2015) (PubMed).

Wang, Li, Cheng, Zhang, Narsinh, Li, Li, Qin, Zhang, Li, Su, Chen, Cao: "Activation of Liver X Receptor Improves Viability of Adipose-Derived Mesenchymal Stem Cells to Attenuate Myocardial Ischemia Injury Through TLR4/NF-?B and Keap-1/Nrf-2 Signaling Pathways." dans: Antioxidants & redox signaling, (2014) (PubMed).

Dalaklioglu, Tasatargil, Kale, Tanriover, Dilmac, Erin: "Metastatic breast carcinoma induces vascular endothelial dysfunction in Balb-c mice: Role of the tumor necrosis factor-? and NADPH oxidase." dans: Vascular pharmacology, Vol. 59, Issue 3-4, pp. 103-11, (2013) (PubMed).

Lagadinou, Sach, Callahan, Rossi, Neering, Minhajuddin, Ashton, Pei, Grose, ODwyer, Liesveld, Brookes, Becker, Jordan: "BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells." dans: Cell stem cell, Vol. 12, Issue 3, pp. 329-41, (2013) (PubMed).

Détails sur CYBB

Antigène: CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

Autre désignation: NOX2/gp91phox

Sujet:

Synonyms: CGD, NOX2, IMD34, AMCBX2, GP91-1, GP91PHOX, p91-PHOX, GP91-PHOX, Cytochrome b-245 heavy chain, CGD91-phox, Cytochrome b(558) subunit beta, Cytochrome b558 subunit beta, Heme-binding membrane glycoprotein gp91phox, NADPH oxidase 2, Neutrophil cytochrome b 91 kDa polypeptide, Superoxide-generating NADPH oxidase heavy chain subunit, p22 phagocyte B-cytochrome, CYBB

Background: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.

ID gène: 1536

UniProt: P04839