Kallikrein 1 anticorps (AA 25-261) (Biotin)

N° du produit ABIN8003828

Cet anticorps Lapin Polyclonal détecte spécifiquement Kallikrein 1 dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour Kallikrein 1 anticorps (AA 25-261) (Biotin) (ABIN8003828)

Antigène: Kallikrein 1 (KLK1)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 1 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Kallikrein 1 anticorps (Biotin)

Épitope: AA 25-261

Fonction: Anti-Kallikrein 1/KLK1 Antibody Biotin Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived mouse KLK1 recombinant protein (Position: I25-D261).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Kallikrein 1

Antigène: Kallikrein 1 (KLK1)

Autre désignation: KLK1

Sujet:

Background: KLK1 (KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

Gene Full Name: kallikrein 1

Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

ID gène: 16612

UniProt: P15947

Pathways: Système du Complément