Kallikrein 10 anticorps (C-Term) (APC)

N° du produit ABIN8003846

Cet anticorps Lapin Polyclonal détecte spécifiquement Kallikrein 10 dans FACS. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour Kallikrein 10 anticorps (C-Term) (APC) (ABIN8003846)

Antigène: Kallikrein 10 (KLK10)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 10 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-Kallikrein 10 anticorps (APC)

Épitope: C-Term

Fonction: Anti-Kallikrein 10/KLK10 Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Kallikrein 10.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Kallikrein 10

Antigène: Kallikrein 10 (KLK10)

Autre désignation: KLK10

Sujet:

Background: KLK10 (kallikrein-related peptidase 10) also known as kallikrein 10, PRSSL1 or NES1, belongs to the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers.KLK10 also contains 12 conserved cysteines in its protease domain that are expected to form 6 disulfide bonds, as in other serine proteases. RT-PCR detected variable levels of KLK10 expression in nearly all of the 35 adult and fetal tissues examined. The KLK10 gene contains 6 exons, the first of which is noncoding. By fluorescence in situ hybridization, Polikoff et al. (1997) mapped the PRSSL1 gene to 19q13.3. By genomic sequence analysis, Gan et al. (2000) mapped the KLK10 gene within the KLK gene cluster on chromosome 19q13. This cluster includes 13 KLK genes and 5 pseudogenes.

Gene Full Name: kallikrein related peptidase 10

Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

ID gène: 5655

UniProt: O43240

Pathways: Système du Complément