Kallikrein 7 anticorps (AA 30-238) (Fluoro550)

N° du produit ABIN8003919

L’anticorps anti-Kallikrein 7 Polyclonal Lapin est utilisé pour la détection de Kallikrein 7 dans des échantillons de Rat. Il a été validé pour FACS.

Aperçu rapide pour Kallikrein 7 anticorps (AA 30-238) (Fluoro550) (ABIN8003919)

Antigène: Kallikrein 7 (KLK7)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 7 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-Kallikrein 7 anticorps (Fluoro550)

Épitope: AA 30-238

Fonction: Anti-Klk7 Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived rat Klk7 recombinant protein (Position: K30-N238).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Kallikrein 7

Antigène: Kallikrein 7 (KLK7)

Autre désignation: Klk7

Sujet:

Background: Kallikrein-related peptidase 7 (KLK7) is a serine protease that in humans is encoded by the KLK7 gene. KLK7 is a chymotrypsin-like serine protease of the member of peptidase S1 family. It is synthesized with a signal peptide of 22 amino acids (aa 1-22) and a propeptide region (aa 23-29) that are subsequently cleaved to generate the mature form. Human KLK7 displays about 40 to 60 % amino acid homology with other members of the family. It cleaves proteins with aromatic side chains in the P1 position. KLK7 is abundantly expressed in the skin and is also present in the brain, mammary gland, cerebellum, spinal cord, and kidney. Lower levels of expression have been reported in in salivary glands, uterus, thymus, thyroid, placenta, trachea, and testis. Its levels are shown to be up-regulated in ovarian carcinoma, especially late-stage serous carcinoma. Less differentiated tumors of more advanced stage show higher level KLK7 expression. KLK7 activity is inhibited by zinc and copper ions

Gene Full Name: kallikrein 1

ID gène: 292852

UniProt: P36373

Pathways: Système du Complément