Kallikrein 8 anticorps (AA 33-260) (Fluoro594)
Aperçu rapide pour Kallikrein 8 anticorps (AA 33-260) (Fluoro594) (ABIN8003931)
Antigène
Voir toutes Kallikrein 8 (KLK8) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 33-260
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Fonction
- Anti-Kallikrein 8/KLK8 Antibody Fluoro594 Conjugated
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- Human Kallikrein 8 shares 74%,73.1% amino acid (aa) sequence identity with mouse,rat Kallikrein 8,respectively.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human Kallikrein 8 recombinant protein (Position: V33-G260). Human Kallikrein 8 shares 74% and 73.1% amino acid (aa) sequence identity with mouse and rat Kallikrein 8, respectively.
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Isotype
- IgG
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Indications d'application
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Date de péremption
- 12 months
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- Kallikrein 8 (KLK8)
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Autre désignation
- KLK8
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Sujet
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Background: Kallikrein-8 is a protein that in humans is encoded by the KLK8 gene. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Gene Full Name: kallikrein related peptidase 8
Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.
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ID gène
- 11202
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UniProt
- O60259
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Pathways
- Système du Complément
Antigène
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