KIAA1524 anticorps (C-Term) (Fluoro488)

N° du produit ABIN8004347

Cet anticorps Lapin Polyclonal détecte spécifiquement KIAA1524 dans FACS. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour KIAA1524 anticorps (C-Term) (Fluoro488) (ABIN8004347)

Antigène: KIAA1524

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIAA1524 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-KIAA1524 anticorps (Fluoro488)

Épitope: C-Term

Fonction: Anti-p90 Autoantigen/KIAA1524 CIP2A Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by three amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human KIAA1524, different from the related mouse sequence by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur KIAA1524

Antigène: KIAA1524

Autre désignation: CIP2A

Sujet:

Background: Protein CIP2A, also known as cancerous inhibitor of PP2A  (CIP2A), is a protein that in humans is encoded by the KIAA1524 gene. CIP2A is required for the malignant cellular growth and for in vivo tumor formation. In accordance with the oncogenic role of CIP2A, overexpression of CIP2A promotes Ras-elicited cell growth and transforms immortalized human cells (HEK-TERVs). More recently CIP2A has been shown to regulate phosphorylation and activity of many other oncoproteins and to drive malignant cell growth and tumorigenesis in various human cancer types. Importantly, CIP2A deficient mice are viable, suggesting that targeting of oncogenic function of CIP2A would not result in serious side-effects.

Gene Full Name: cellular inhibitor of PP2A

ID gène: 57650

UniProt: Q8TCG1