KIF7 anticorps (Middle Region) (Biotin)
Aperçu rapide pour KIF7 anticorps (Middle Region) (Biotin) (ABIN8004510)
Antigène
Voir toutes KIF7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Middle Region
-
Fonction
- Anti-KIF7 Antibody Biotin Conjugated
-
Réactivité croisée (Details)
- No cross-reactivity with other proteins.
-
Homologie
- identical to the related mouse sequences.
-
Purification
- Immunogen affinity purified.
-
Immunogène
- A synthetic peptide corresponding to a sequence in the middle region of human KIF7, identical to the related mouse sequences.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
-
Date de péremption
- 12 months
-
-
- KIF7 (Kinesin Family Member 7 (KIF7))
-
Autre désignation
- KIF7
-
Sujet
-
Background: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
Gene Full Name: kinesin family member 7
-
ID gène
- 374654
-
UniProt
- Q2M1P5
-
Pathways
- Signalisation Hedgehog
Antigène
-