LDHB anticorps (AA 237-334) (Fluoro488)

N° du produit ABIN8004920

Cet anticorps Lapin Polyclonal détecte spécifiquement LDHB dans FACS. Il présente une réactivité avec des échantillons de Humain, Rat, Souris et Singe.

Aperçu rapide pour LDHB anticorps (AA 237-334) (Fluoro488) (ABIN8004920)

Antigène: LDHB (Lactate Dehydrogenase B (LDHB))

Reactivité: Humain, Rat, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LDHB est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-LDHB anticorps (Fluoro488)

Épitope: AA 237-334

Fonction: Anti-Lactate Dehydrogenase B/LDHB Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: coli-derived human LDHB recombinant protein (Position: E237-L334). Human LDHB shares 98% amino acid (aa) sequence identity with both mouse,rat LDHB.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human LDHB recombinant protein (Position: E237-L334). Human LDHB shares 98% amino acid (aa) sequence identity with both mouse and rat LDHB.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur LDHB

Antigène: LDHB (Lactate Dehydrogenase B (LDHB))

Autre désignation: LDHB

Sujet:

Background: The LDHB gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

Gene Full Name: lactate dehydrogenase B

ID gène: 3945

UniProt: P07195

Pathways: L'effet Warburg