Lamin B1 anticorps (AA 266-583)
Aperçu rapide pour Lamin B1 anticorps (AA 266-583) (ABIN8005016)
Antigène
Voir toutes Lamin B1 (LMNB1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 266-583
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Fonction
- Anti-Lamin B1/LMNB1 Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- Human Lamin B1 shares 95.9%,95% amino acid (aa) sequence identity with mouse,rat Lamin B1,respectively.
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Attributs du produit
- Anti-Lamin B1/LMNB1 Antibody. Tested in Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human Lamin B1 recombinant protein (Position: Q266-C583). Human Lamin B1 shares 95.9% and 95% amino acid (aa) sequence identity with mouse and rat Lamin B1, respectively.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.5 μg/mL Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL Immunocytochemistry/Immunofluorescence, 5 μg/mL Immunoprecipitation, 0.5-2 μg/mL Flow Cytometry (Fixed), 1-3 μg/1x106 cells
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- Lamin B1 (LMNB1)
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Autre désignation
- LMNB1
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Sujet
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Background: Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.
Gene Full Name: lamin B1
Sequence Similarities: Belongs to the intermediate filament family.
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Poids moléculaire
- 67 kDa
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ID gène
- 4001
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UniProt
- P20700
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Pathways
- Apoptose, Caspase Cascade in Apoptosis
Antigène
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