Lamin B2 anticorps (AA 128-585) (APC)

N° du produit ABIN8005035

L’anticorps anti-Lamin B2 Polyclonal Lapin est utilisé pour la détection de Lamin B2 dans des échantillons de Humain et Rat. Il a été validé pour FACS.

Aperçu rapide pour Lamin B2 anticorps (AA 128-585) (APC) (ABIN8005035)

Antigène: Lamin B2 (LMNB2)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lamin B2 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-Lamin B2 anticorps (APC)

Épitope: AA 128-585

Fonction: Anti-Lamin B2/LMNB2 Antibody APC Conjugated

Homologie: Human LMNB2 shares 81.8% amino acid (aa) sequence identity with mouse LMNB2.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Lamin B2/LMNB2 recombinant protein (Position: L128-E585). Human LMNB2 shares 81.8% amino acid (aa) sequence identity with mouse LMNB2.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Lamin B2

Antigène: Lamin B2 (LMNB2)

Autre désignation: Lamin B2/LMNB2

Sujet:

Background: Lamin B2 is a protein that in humans is encoded by the LMNB2 gene. This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.

Gene Full Name: lamin B2

ID gène: 84823

UniProt: Q03252

Pathways: Apoptose, Caspase Cascade in Apoptosis