LIM Domain Kinase 1 anticorps (C-Term)
Aperçu rapide pour LIM Domain Kinase 1 anticorps (C-Term) (ABIN8006062)
Antigène
Voir toutes LIM Domain Kinase 1 (LIMK1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
-
-
Épitope
- C-Term
-
Fonction
- Anti-LIMK1 Antibody
-
Specificité
- No cross reactivity with other proteins.
-
Réactivité croisée (Details)
- No cross-reactivity with other proteins
-
Homologie
- different from the related mouse sequence by three amino acids,and from the related rat sequence by two amino acids.
-
Attributs du produit
- Anti-LIMK1 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
-
Purification
- Immunogen affinity purified.
-
Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminus of human LIMK1 , different from the related mouse sequence by three amino acids, and from the related rat sequence by two amino acids.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
-
-
- LIM Domain Kinase 1 (LIMK1)
-
Autre désignation
- LIMK1
-
Sujet
-
Background: LIM domain kinase 1?is an?enzyme?that in humans is encoded by the?LIMK1?gene. There are approximately 40 known eukaryotic LIM proteins, so named for the?LIM domains?they contain. LIM domains are highly conserved?cysteine-rich structures containing 2?zinc fingers. Although zinc fingers usually function by binding to?DNA?or?RNA, the LIM motif probably mediates?protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2?N-terminal?LIM motifs, a central?PDZ domain, and a?C-terminal?protein kinase?domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development.
Gene Full Name: LIM domain kinase 1
-
Poids moléculaire
- 72 kDa
-
ID gène
- 3984
-
UniProt
- P53667
-
Pathways
- Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
Antigène
-