LOXL2 anticorps (C-Term) (FITC)

N° du produit ABIN8007147

L’anticorps anti-LOXL2 Polyclonal Lapin est utilisé pour la détection de LOXL2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour LOXL2 anticorps (C-Term) (FITC) (ABIN8007147)

Antigène: LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LOXL2 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-LOXL2 anticorps (FITC)

Épitope: C-Term

Fonction: Anti-LOXL2 Antibody FITC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse,rat sequences by four amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human LOXL2, different from the related mouse and rat sequences by four amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur LOXL2

Antigène: LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

Autre désignation: LOXL2

Sujet:

Background: Lysyl oxidase homolog 2?is an?enzyme?that in humans is encoded by the?LOXL2?gene. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.?LOXL2 can also crosslink?collagen type IV?and hence influence the sprouting of new?blood?vessels.

Gene Full Name: lysyl oxidase like 2

ID gène: 4017

UniProt: Q9Y4K0

Pathways: Chromatin Binding